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Online Liposome Extruder

Description: Genizer Online Liposome Extruders is high pressure homogenizer or pump online driven, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery; Temperature control is available.
Catalog Number: Cat.GOE
Price:
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$1,000.00   Login for Discount
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  • Catalog No.:
    GOE-25mL GOE-200mL GOE-1000mL GOE-8L GOE-20L GOE-8L×2 GOE-8L×4 GOE-8L×8
  • Warranty:
    Standard 1 year
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  • Description
Description:
Genizer Online Liposome Extruders can be connected with sanitary pump, high pressure homogenizer and it is temperature controlled, from testing to manufacture production of pharmaceuical liposome such as Doxorubicin, Irinotecan and Paclitaxel. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The Online Liposome Extruder is virtually no dead-volume and easily cleaned and suitable for sterilization. The Genizer Online Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters with defined pore size. The Genizer Online Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals.
 
Application:
Liposome Extrusion
 
Performance:
No Dead Volume
Online Extruder can control the temperature of Extrusion
 
Specification
Catalog No. GOE-25mL GOE-200mL GOE-1000mL GOE-8L GOE-20L
Sample Size 25mL 200mL 1000mL 8000mL 20000mL
Cooling Jacketed Jacketed Jacketed Jacketed Jacketed
Dimensions 10cm×10cm×8cm 13cm×13cm×9cm 18cm×18cm×10cm 30cm×25cm×25cm 45cm×40cm×30cm
Weight 1kg 2kg 5kg 25kg 90kg
Min. Sample Size 5mL 10mL 100mL 500mL 1000mL
Application Liposome formulation up to production scale
Max. Pressure 3,000 psi-6,000 psi
Temp. Limit 80ºC (176ºF)
Power Type High pressure pump or High pressure homogenizer
Nano-membrane Track-etched membrane
Cleaning Flush to clean/CIP/SIP
Sterilizing Whole unit autoclavable
 
Standard Features
Parts 1) Liposome Online Extruder
2) 10 pieces of 100nm membrane
Filter Support Jacketed Filter Support with Pagoda inlet and outlet 
Inlet Type 3/8" High pressure coupling
Outlet Type 3/8" High pressure coupling
Handle Handle for GOE-800mL, GOE-3000mL and GOE-10000mL
Nano membrane 100nm track-etched polycarbonate membrane
Compatibility Some Parts are compatible with Lipex™ in Northern Lipids
Product material 316L stainless steel, Viton
Material standard Pharmaceutical Grade; Compliance with FDA and GMP sanitary standards
Warranty 1 year against any manufacturing defects
 
Option Features
Detector 10,000psi sanitary Pressure Gauge with adaptor, Pressure transducer, Temperature transducer
Power Sanitary High pressure piston pump/hand pump
Inlet Type Tri-clamp or Luer
Outlet Type Tri-clamp or Luer
Nano membrane 30nm, 50nm, 80nm, 100nm, 200nm, 400nm, 800nm, 1000nm, 2μm, 5μm, 10μm, 20μm, 30μm track-etched membrane (25mm, 47mm, 90mm, 150mm, 293mm)
Multi Extruder Parallel or Series connection of Multi Extruder
URS for Liposome Extruders System.doc