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Jacketed Liposome Extruder

Description: Genizer Jacketed Liposome Extruders is compressed air driven, temperature controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery.
Catalog Number: Cat.Jacketed Liposome Extruder
Price:
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$3,000.00   Login for Discount
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  • Capacity:
    10mL 100mL 800mL 3000mL 10L
  • Gas Connection:
    CGA580 (USA) G5/8 (UK, CN) DIN477 (GE) NF E 29-650/C (FR) UNI4409 (IT)
  • Warranty:
    Standard 1 year 2 year 3 year 4 year 5 year
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  • Description
  • How to Use

Description: Genizer Jacketed Liposome Extruders is compressed air driven, temperature controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery.

The Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters with defined pore size. It is relatively gentle, exposing the formulation to moderate pressures up to 1,500 psi at controlled temperatures. The Genizer Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals.

Specifications

Catalog No. Gextruder-10ml, Gextruder-100ml, Gextruder-800ml, Gextruder-3000ml, Gextruder-10000ml, Gextruder-Customize
Description Jacketed Temperature-control Liposome Extruder
Min. Sample Size 5ml, 20ml, 200ml, 500ml, 10,000ml, TBD
Temperature Limit 80ºC (176ºF)
Power Requirements Compressed Gas
Feed Reservoir 10ml, 100ml, 800ml, 3000ml, 10,000ml, TBD
Cleaning Flush to clean
Sterilizing Whole unit autoclavable
Max. Pressure 3,000psi
Application Liposome formulation up to production scale

Standard Features

Inlet type 3/8" High pressure coupling
Outlet type 3/8" High pressure coupling
Feed Reservoir Temperature control jacketed cylinder
Nitrogen Line G5/8" - 14 TPI BSP inlet Nitrogen High pressure soft tubing
Nano membrane 100nm track-etched polycarbonate membrane
Compatibility Some Parts are compatible with Lipex™ in Northern Lipids
Product material 316L stainless steel, Viton
Material standard Compliance with FDA and GMP sanitary standards
Warranty 1 year against any manufacturing defects

Option Features

Detector Pressure gauge, Pressure transducer, Temperature transducer
Inlet type Tri-clamp or Luer
Outlet type Tri-clamp or Luer
Multi Extruder Parallel or Series connection of Multi Extruder
Nano membrane 30, 50, 80, 200, 400, 800nm track-etched membrane

 
1) The Jacketed Liposome Extruder use the compressed air such as Nitrogen (N2) as the pressure souce


1. Add liposome membrane
2. Add the Liposome crude sample from the inlet
3. Connect Gas Connection with Regulator
4. Open the Nitrogen and pressure the Liposome crude sample through the Membrane

2) Please select the suitable the Gas connection for your Nigrogen cylinder
 
CGA580  (USA) United States
G5/8  (UK,CN) United Kingdom, China
DIN477 (GE) Germany
NF E 29-650/C (FR) France
UNI4409 (IT) Italy


3) Warning

1) Always use Regulator, please get regulator from your gas supplier
2) Before open the extruder, be sure to shut down the Gas and open the Relief valve
3) DO NOT  point the inlet of the Liposome extruder to the any personnel and object which may induce the safety issue and property loss
4) The user should be  responsible for the violation of the clause and recommendation besides any other unsafe practices.